Most white Americans agreed that Western expansion was essential to the health of the nation. But what should be done against slavery in the West? The question of Missouri`s final admission arose at the 1820-1821 meeting. The struggle was revived by a clause in the new Constitution of Missoure dating back to 1820, which requires the exclusion of "free negroes and mulaats" from the state. The influence of Kentucky Senator Henry Clay, known as the "Grand Compromiser," was eventually adopted if the exclusion clause in the Missouri Constitution "should never be construed as authorizing the passage of a law," which undermines the privileges and immunities of an American citizen. This deliberately ambiguous provision is sometimes referred to as the second compromise on Missouri.  The Dred Scott v. Sandford The 1857 Supreme Court decision found that the Missouri compromise was unconstitutional. Justice Chief Roger Taney and six other justices ruled that the Missouri compromise was illegal because Congress did not have the power to ban slavery in the territories, and the slave masters were granted fifth-amendment title to property rights. African-Americans were clearly opposed to slavery and news of some congressional opposition to its expansion spread to slave communities. Denmark Vesey, a free black man who lives in Charleston, South Carolina, made the most dramatic use of white discord over the future of slavery in the West. Vesey cited the Bible and congressional debates on the Missouri issue to denounce the slavery of the chair of the African Methodist Episcopal Church, where he was a lay priest.
In 1822, with a prominent ally named Gullah Jack, Vesey organized a slave insurrection that planned to conquer Charleston`s arsenal and conquer the city long enough for his black population to escape to the Black Free Republic of Haiti. The majorities of the House have not broken down into political domination. The point of rotation and attainment of diesatose lay in the Senate, where the constitutional compromise of 1787 had provided for two senators per state, regardless of its population. The South, with its free population smaller than the North, has benefited from this regulation. Since 1815, the division of senate sections has been reached by twin admissions that left the North and South in 11 states during the application of the Missouri Territory.  On the agricultural front, the Missouri River country, which was to form this new state, had no prospect as a major cotton producer.